Senior Informatics Architect

TetraScience

IT

San Mateo, CA, USA · Boston, MA, USA

Posted on Oct 30, 2026

1. Informatics Engineering & Service Architecture

* Apply Lessons Learned From Domain Leaders: Bring practical, everyday lessons learned and experiences from other areas, domains and professions to this problem space. * Engineer Semantic Services: Co-design and build the Service-Oriented Architecture (SOA) components responsible for the lifecycle of semantic data. Your software enables ingestion, abstraction, curation, and publication, versioning, governance & distribution of semantic resources—encompassing formal biomedical ontologies, standard terminologies, and reference lists—integrating them directly into data-in-flight services. * Data Engineering for Continuous Modeling: Develop and deploy ETL pipelines that lift instance-level data into formal vocabularies. You will ensure these pipelines capture the nuanced aspects of the model, including complex relationships, properties, and constraints. * Living Ontology Development: Build services that project formal semantic meaning across the Tetra ecosystem, helping to formalize a "living," real-world ontology that evolves with our data and its usage. * Partner as a Force Multiplier: Collaborate with Scientific Data Engineers, Architects, and Business Leads to integrate semantic artifacts technically. You will provide subject matter expertise, coaching, and training on the governance of controlled vocabularies, ensuring formal semantics and structure are applied consistently across platform applications.

3. Standardization & Governance

* Vocabulary Management: Develop software enabling management of the full lifecycle of our formal vocabularies. You will implement robust systems for versioning, deprecating, and migrating vocabularies across our customer base to ensure seamless operations. * Engineering Mentorship: Serve as the "Informatics SME" for the engineering organization. You will partner with and mentor technical team members—ranging from pure software engineers to scientists—on how to leverage semantic artifacts to provide data with formal definitions, meaning, and context. * Data Exchange Standards: Co-design the "handshake" protocols for data exchange between platform components. You will iteratively develop these standards to ensure that data leaving one system is deterministically understood by another, handling the complex mapping and transformation logic required for true syntactic and semantic interoperability.